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Professor, Department of Paediatrics Alberta Children's Hospital
Mailing Address: Alberta Children's Hospital, 2888 Shaganappi Trail N.W., Calgary, AB T3B 6A8
Dr Buchhalter's main research interests are risk factors for epilepsy surgery outcome in children, ketogenic diet, trials of new anti-epileptic drugs, epilepsy genetics, application of informatics methods to epilepsy classification and terminology as well as implementation of outcomes and incorporation of translational research to optimize the outcomes of children with epilepsy He also participates in several national committees in the United States including serving as chair of the American Epilepsy Society SUDEP (Sudden Unexpected Death in EPilepsy) Task Force and the Medical Economics and Management Committee of the American Academy of Neurology. He serves on the editorial boards of Pediatric Neurology, Clinical Neurology News and Epilepsy Currents, in addition to being a reviewer for multiple neurology and epilepsy journals.
The Hospital for Sick Children
Senior Scientist,Psychiatry Research Institute
Senior Scientist Neurosciences & Mental Health, University of Toronto
Dr. Schachar trained in medicine at the University of Toronto and in psychiatry at McMaster University, Hamilton. A period of post doctoral training followed at the Institute of Psychiatry, University of London, England under the supervision of Professor Sir Michael Rutter. Schachar returned to The Hospital for Sick Children, where he initiated a clinical-research program in Neuropsychiatry, established a model clinical research program (Neuropsychiatry Team) and set up an active laboratory. Dr. Schachar’s work is featured in leading North American and European Psychiatric journals such as the American Journal of Psychiatry, the Journal of the American Academy of Child and Adolescent Psychiatry, Human Brain Mapping, and the Journal of Child Psychiatry and Psychology.
His national role is evident in positions such as the Editorship of the Special Issue on Child and Adolescent Psychiatry, Canadian Journal of Psychiatry (1998-2000) and his selection by The Centre of Excellence for Early Childhood Development (CEECD) for one of 10 best scientific papers, published in 2002 by Canadian researchers, on early childhood development.
Director, The Centre for Applied Genomics, The Hospital for Sick Children
Known for contributions to discovering the phenomena of global copy number variation (CNVs) of DNA and genes as the most abundant type of genetic variation in the human genome, Dr. Scherer leads one of Canada's busiest laboratories. His group has discovered numerous disease susceptibility genes and most recently has defined CNV and other genetic factors underlying autism. He collaborated with Craig Venter's team to decode human chromosome 7 and to generate the first genome sequence of an individual. Some 300 scientific papers document his work (cited >20,000 times). He sits on the Scientific Advisory Board of Combimatrix Diagnostics and Autism Speaks, and he is on the Board of Trustees of Genome Canada and the Human Genome Organization (HUGO). He is the Director of the McLaughlin Centre and The Centre for Applied Genomics.
"Adherence and the socio-cultural aspects of medicine interest me: Based on this I developed, in collaboration with medical anthropology and educational psychology, a Clinical Comprehensive Sleep Assessment concept
(#1) and began to transform physiological knowledge
(#2) with questions of sleep to health
(#3, #5) and care management
(#4). I developed a virtual sleep lab, in collaboration with the Cognitive Systems Lab at UBC, where we utilize overnight-sleep-video systems for screening ‘visible’ and ‘recognizable’ sleep disorders in children with ASD, FASD, Cerebral Palsy and other NDDs in their natural setting. Based on our research, the Inter. RLS Consensus Group has included children with NDD in their recent Consensus Statement.
References Dr. Osman Ipsiroglu (nominated PI; Site Lead British Columbia)
Expertise: Developmental Paediatrics, Phenotyping & Sleep Medicine, Comprehensive Sleep Assessments of Children with NDD (#1-3), Neurophysiology (#4), Health Care Management (#5)
1. Ipsiroglu, O.S., McKellin, W., Carey, N., & Loock, C. (2013). They live silently in terror: Let us Talk Night-Time-Related Quality-of-Life for Children and Adolescents with Neurodevelopmental Disorders. Social Science & Medicine, 79, 76-83. doi: 10.1016/j.socscimed.2012.10.027.
In this paper, I analyzed the question, why sleep has not been identified as a quality of life issue in paediatric chronic care? The study highlights deficits in the diagnostic recognition of chronic SPs among children with chronic NDD and proposes a clinical practice strategy, based on therapeutic emplotment that incorporates patients’ and parents' contributions in recognizing SPs and related sequelae in designing appropriate treatment and care.
2. Jan, J.E., Asante, K.O., Conry, J.L., Fast, D.K., Bax, M.C.O., Ipsiroglu, O.S., Bredberg, E., Loock, C.A., & Wasdell, M.B. (2010). Sleep Health Issues for Children with FASD: Clinical Considerations. International Journal of Pediatrics, 2010, 1-7. doi:10.1155/2010/639048.
3. Jan, J.E., Owens, J., Weiss, M., Johnson, K., Wasdell, M.B., Freeman, R., & Ipsiroglu, O.S. (2008). Sleep Hygiene for Children with Neurodevelopmental Disabilities. Pediatrics, 122(6), 1343-1350. doi:10.1542/peds.2007-3308.
The articles #2/#3 describe the combined clinical experience of a multidisciplinary group of professionals on the sleep disturbances of children with FASD and NDD focusing on sleep hygiene interventions; both articles have been written in order to stimulate the discussion about the much needed evidence- based approach to sleep problems of children with FASD and NDD, respectively.
4. Jan, J.E., Bax, M.C.O., Owens, J., Ipsiroglu, O.S., & Wasdell, M.B. (2012). Neurophysiology of Circadian Rhythm Disorders of Children with
Neurodevelopmental Disabilities. European Journal of Paediatric Neurology, 16(5), 403-412. doi: 10.1016/j.ejpn.2012.01.002.
This article reviews circadian rhythm sleep disorders of children with NDD, as sleep disturbances frequently occur in children with ND, but they are misunderstood and under diagnosed.
5. Ipsiroglu, O.S., Freeman, R., Laswick, A., McKellin, W., Milner, R., Mitton, C., Wasdell, M.B., Wensley, D., & Jan, J.E. (2009). How to Approach Paediatric Sleep Medicine in BC? A Consensus Paper. BCMJ, 50(9), 512-516. Retrieved from http://www.bcmj.org/sites/default/files/BCMJ_50Vol9_core3.pdf.
In order to determine the pediatric sleep medicine needs in BC, we organized a consensus meeting and based on the published consensus we advocate for improved services in BC for children with NDD.
updated: September 30, 2013